Publications

  1. Health-related quality of life in people with predementia Alzheimer's disease, mild cognitive impairment or dementia measured with preference-based instruments: a systematic literature review. Landeiro, F, Mughal, S, Walsh, K, Nye, E, Morton, J, Williams, H, Ghinai, I, Castro, Y, Leal, J, Roberts, N, Wace, H, Handels, R, Lecomte, P, Gustavsson, A, Roncancio-Diaz, E, Belger, M, Jhuti, GS, Bouvy, JC, Potashman, MH, Tockhorn-Heidenreich, A, Gray, AM, ROADMAP consortium. PubMed PMID:33208190
  2. A validation study of the CarerQol instrument in informal caregivers of people with dementia from eight European countries. Voormolen, DC, van Exel, J, Brouwer, W, Sköldunger, A, Gonçalves-Pereira, M, Irving, K, Bieber, A, Selbaek, G, Woods, B, Zanetti, O, Verhey, F, Wimo, A, Handels, RLH, Actifcare Consortium. PubMed PMID:33113082
  3. Obtaining EQ-5D-5L utilities from the disease specific quality of life Alzheimer's disease scale: development and results from a mapping study. Rombach, I, Iftikhar, M, Jhuti, GS, Gustavsson, A, Lecomte, P, Belger, M, Handels, R, Castro Sanchez, AY, Kors, J, Hopper, L, Olde Rikkert, M, Selbæk, G, Stephan, A, Sikkes, SAM, Woods, B, Gonçalves-Pereira, M, Zanetti, O, Ramakers, IHGB, Verhey, FRJ, Gallacher, J, Actifcare Consortium,, LeARN Consortium,, Landeiro, F, Gray, AM, ROADMAP Consortium. PubMed PMID:33068236
  4. Profiles of Met and Unmet Needs in People with Dementia According to Caregivers' Perspective: Results from a European Multicenter Study. Janssen, N, Handels, RL, Köhler, S, Gonçalves-Pereira, M, Marques, MJ, Irving, K, Hopper, L, Bieber, A, Orrell, M, Selbæk, G, Michelet, M, Wimo, A, Zanetti, O, Portolani, DM, Woods, B, Jelley, H, Evers, SMAA, Verhey, FRJ, Actifcare Consortium. PubMed PMID:32674953
  5. Quantifying and Describing the Natural History and Costs of Alzheimer's Disease and Effects of Hypothetical Interventions. Wimo, A, Handels, R, Winblad, B, Black, CM, Johansson, G, Salomonsson, S, Eriksdotter, M, Khandker, RK. PubMed PMID:32390617
  6. Controlling for selective dropout in longitudinal dementia data: Application to the SveDem registry. Handels, R, Jönsson, L, Garcia-Ptacek, S, Eriksdotter, M, Wimo, A. PubMed PMID:32202077
  7. Duration of Care Trajectories in Persons With Dementia Differs According to Demographic and Clinical Characteristics. Janssen, O, Vos, SJB, Handels, R, Vermunt, L, Verheij, R, Verhey, FRJ, van Hout, H, Visser, PJ, Joling, KJ. PubMed PMID:32113914
  8. Is there equity in initial access to formal dementia care in Europe? The Andersen Model applied to the Actifcare cohort. Kerpershoek, L, de Vugt, M, Wolfs, C, Orrell, M, Woods, B, Jelley, H, Meyer, G, Bieber, A, Stephan, A, Selbaek, G, Michelet, M, Wimo, A, Handels, R, Irving, K, Hopper, L, Gonçalves-Pereira, M, Balsinha, C, Zanetti, O, Portolani, D, Verhey, F, Actifcare Consortium. PubMed PMID:31647572
  9. A validation study of the ICECAP-O in informal carers of people with dementia from eight European Countries. Perry-Duxbury, M, van Exel, J, Brouwer, W, Sköldunger, A, Gonçalves-Pereira, M, Irving, K, Meyer, G, Selbæk, G, Woods, B, Zanetti, O, Verhey, F, Wimo, A, Handels, RLH, Actifcare Consortium. PubMed PMID:31595452
  10. Assessing cost-effectiveness of early intervention in Alzheimer's disease: An open-source modeling framework. Green, C, Handels, R, Gustavsson, A, Wimo, A, Winblad, B, Sköldunger, A, Jönsson, L. PubMed PMID:31402324
  11. Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype. Vermunt, L, Sikkes, SAM, van den Hout, A, Handels, R, Bos, I, van der Flier, WM, Kern, S, Ousset, PJ, Maruff, P, Skoog, I, Verhey, FRJ, Freund-Levi, Y, Tsolaki, M, Wallin, ÅK, Olde Rikkert, M, Soininen, H, Spiru, L, Zetterberg, H, Blennow, K, Scheltens, P, Muniz-Terrera, G, Visser, PJ, Alzheimer Disease Neuroimaging Initiative, AIBL Research Group, ICTUS/DSA study groups. PubMed PMID:31164314
  12. Do caregiver profiles predict the use of dementia care services? Findings from the Actifcare study. Kerpershoek, L, Woods, B, Wolfs, C, Verhey, F, Jelley, H, Bieber, A, Stephan, A, Michelet, M, Selbaek, G, Handels, R, Wimo, A, Hopper, L, Irving, K, Marques, MJ, Gonçalves-Pereira, M, Portolani, E, Zanetti, O, de Vugt, M, Actifcare Consortium. PubMed PMID:30518244
  13. Impact of Untimely Access to Formal Care on Costs and Quality of Life in Community Dwelling People with Dementia. Janssen, N, Handels, RL, Sköldunger, A, Woods, B, Jelley, H, Edwards, RT, Orrell, M, Selbæk, G, Røsvik, J, Gonçalves-Pereira, M, Marques, MJ, Zanetti, O, Portolani, E, Irving, K, Hopper, L, Meyer, G, Bieber, A, Stephan, A, Kerpershoek, L, Wolfs, CAG, de Vugt, ME, Verhey, FRJ, Wimo, A, Consortium Actifcare. PubMed PMID:30400096
  14. Quality of Life, Care Resource Use, and Costs of Dementia in 8 European Countries in a Cross-Sectional Cohort of the Actifcare Study. Handels, RLH, Sköldunger, A, Bieber, A, Edwards, RT, Gonçalves-Pereira, M, Hopper, L, Irving, K, Jelley, H, Kerpershoek, L, Marques, MJ, Meyer, G, Michelet, M, Portolani, E, Røsvik, J, Selbaek, G, Stephan, A, de Vugt, M, Wolfs, C, Woods, B, Zanetti, O, Verhey, F, Wimo, A, Actifcare consortium. PubMed PMID:30372674
  15. Cognitive behavioural therapy for anxiety disorders in Parkinson's disease: Design of a randomised controlled trial to assess clinical effectiveness and changes in cerebral connectivity. Mulders, AEP, Moonen, AJH, Dujardin, K, Kuijf, ML, Duits, A, Flinois, B, Handels, RLH, Lopes, R, Leentjens, AFG. PubMed PMID:30097133
  16. Systematic literature review of methodologies and data sources of existing economic models across the full spectrum of Alzheimer's disease and dementia from apparently healthy through disease progression to end of life care: a systematic review protocol. Karagiannidou, M, Wittenberg, R, Landeiro, FIT, Park, AL, Fry, A, Knapp, M, Gray, AM, Tockhorn-Heidenreich, A, Castro Sanchez, AY, Ghinai, I, Handels, R, Lecomte, P, Wolstenholme, J, ROADMAP Group. PubMed PMID:29884696
  17. Measuring quality of life of people with predementia and dementia and their caregivers: a systematic review protocol. Landeiro, F, Walsh, K, Ghinai, I, Mughal, S, Nye, E, Wace, H, Roberts, N, Lecomte, P, Wittenberg, R, Wolstenholme, J, Handels, R, Roncancio-Diaz, E, Potashman, MH, Tockhorn-Heidenreich, A, Gray, AM, ROADMAP Group. PubMed PMID:29602838
  18. Resource utilisation and costs in predementia and dementia: a systematic review protocol. Landeiro, F, Wace, H, Ghinai, I, Nye, E, Mughal, S, Walsh, K, Roberts, N, Lecomte, P, Wittenberg, R, Wolstenholme, J, Handels, R, Roncancio-Diaz, E, Potashman, MH, Tockhorn-Heidenreich, A, Gray, AM, ROADMAP Group. PubMed PMID:29362261
  19. Cost-Utility of Using Alzheimer's Disease Biomarkers in Cerebrospinal Fluid to Predict Progression from Mild Cognitive Impairment to Dementia. Handels, RLH, Wimo, A, Dodel, R, Kramberger, MG, Visser, PJ, Molinuevo, JL, Verhey, FRJ, Winblad, B. PubMed PMID:29081416
  20. Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. Lewczuk, P, Riederer, P, O'Bryant, SE, Verbeek, MM, Dubois, B, Visser, PJ, Jellinger, KA, Engelborghs, S, Ramirez, A, Parnetti, L, Jack, CR Jr, Teunissen, CE, Hampel, H, Lleó, A, Jessen, F, Glodzik, L, de Leon, MJ, Fagan, AM, Molinuevo, JL, Jansen, WJ, Winblad, B, Shaw, LM, Andreasson, U, Otto, M, Mollenhauer, B, Wiltfang, J, Turner, MR, Zerr, I, Handels, R, Thompson, AG, Johansson, G, Ermann, N, Trojanowski, JQ, Karaca, I, Wagner, H, Oeckl, P, van Waalwijk van Doorn, L, Bjerke, M, Kapogiannis, D, Kuiperij, HB, Farotti, L, Li, Y, Gordon, BA, Epelbaum, S, Vos, SJB, Klijn, CJM, Van Nostrand, WE, Minguillon, C, Schmitz, M, Gallo, C, Lopez Mato, A, Thibaut, F, Lista, S, Alcolea, D, Zetterberg, H, Blennow, K, Kornhuber, J, Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut. PubMed PMID:29076399
  21. Needs and quality of life of people with middle-stage dementia and their family carers from the European Actifcare study. When informal care alone may not suffice. Kerpershoek, L, de Vugt, M, Wolfs, C, Woods, B, Jelley, H, Orrell, M, Stephan, A, Bieber, A, Meyer, G, Selbaek, G, Handels, R, Wimo, A, Hopper, L, Irving, K, Marques, M, Gonçalves-Pereira, M, Portolani, E, Zanetti, O, Verhey, F, Actifcare Consortium. PubMed PMID:29068697
  22. Challenges and recommendations for the health-economic evaluation of primary prevention programmes for dementia. Handels, R, Wimo, A. PubMed PMID:29039976
  23. Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment. Herukka, SK, Simonsen, AH, Andreasen, N, Baldeiras, I, Bjerke, M, Blennow, K, Engelborghs, S, Frisoni, GB, Gabryelewicz, T, Galluzzi, S, Handels, R, Kramberger, MG, Kulczyńska, A, Molinuevo, JL, Mroczko, B, Nordberg, A, Oliveira, CR, Otto, M, Rinne, JO, Rot, U, Saka, E, Soininen, H, Struyfs, H, Suardi, S, Visser, PJ, Winblad, B, Zetterberg, H, Waldemar, G. PubMed PMID:28341066
  24. Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia. Simonsen, AH, Herukka, SK, Andreasen, N, Baldeiras, I, Bjerke, M, Blennow, K, Engelborghs, S, Frisoni, GB, Gabryelewicz, T, Galluzzi, S, Handels, R, Kramberger, MG, Kulczyńska, A, Molinuevo, JL, Mroczko, B, Nordberg, A, Oliveira, CR, Otto, M, Rinne, JO, Rot, U, Saka, E, Soininen, H, Struyfs, H, Suardi, S, Visser, PJ, Winblad, B, Zetterberg, H, Waldemar, G. PubMed PMID:28341065
  25. Predicting progression to dementia in persons with mild cognitive impairment using cerebrospinal fluid markers. Handels, RLH, Vos, SJB, Kramberger, MG, Jelic, V, Blennow, K, van Buchem, M, van der Flier, W, Freund-Levi, Y, Hampel, H, Olde Rikkert, M, Oleksik, A, Pirtosek, Z, Scheltens, P, Soininen, H, Teunissen, C, Tsolaki, M, Wallin, AK, Winblad, B, Verhey, FRJ, Visser, PJ. PubMed PMID:28216393
  26. Caregiver profiles in dementia related to quality of life, depression and perseverance time in the European Actifcare study: the importance of social health. Janssen, EP, de Vugt, M, Köhler, S, Wolfs, C, Kerpershoek, L, Handels, RL, Orrell, M, Woods, B, Jelley, H, Stephan, A, Bieber, A, Meyer, G, Engedal, K, Selbaek, G, Wimo, A, Irving, K, Hopper, L, Gonçalves-Pereira, M, Portolani, E, Zanetti, O, Verhey, FR. PubMed PMID:27869480
  27. Erratum to: Access to timely formal dementia care in Europe: protocol of the Actifcare (ACcess to Timely Formal Care) study. Kerpershoek, L, de Vugt, M, Wolfs, C, Jelley, H, Orrell, M, Woods, B, Stephan, A, Bieber, A, Meyer, G, Engedal, K, Selbaek, G, Handels, R, Wimo, A, Hopper, L, Irving, K, Marques, M, Gonçalves-Pereira, M, Portolani, E, Zanetti, O, Verhey, F, Actifcare Consortium. PubMed PMID:27793151
  28. The Diagnostic and Prognostic Value of Neuropsychological Assessment in Memory Clinic Patients. Jansen, WJ, Handels, RL, Visser, PJ, Aalten, P, Bouwman, F, Claassen, J, van Domburg, P, Hoff, E, Hoogmoed, J, Leentjens, AF, Rikkert, MO, Oleksik, AM, Smid, M, Scheltens, P, Wolfs, C, Verhey, F, Ramakers, IH. PubMed PMID:27716658
  29. Access to timely formal dementia care in Europe: protocol of the Actifcare (ACcess to Timely Formal Care) study. Kerpershoek, L, de Vugt, M, Wolfs, C, Jelley, H, Orrell, M, Woods, B, Stephan, A, Bieber, A, Meyer, G, Engedal, K, Selbaek, G, Handels, R, Wimo, A, Hopper, L, Irving, K, Marques, M, Gonçalves-Pereira, M, Portolani, E, Zanetti, O, Verhey, F, Actifcare Consortium. PubMed PMID:27550084
  30. Combinations of Service Use Types of People With Early Cognitive Disorders. Janssen, N, Handels, RL, Koehler, S, Ramakers, IH, Hamel, RE, Olde Rikkert, MG, Scheltens, P, Bouwman, FH, van der Flier, WM, Wolfs, CA, de Vugt, ME, Evers, SM, Verhey, FR. PubMed PMID:27073042
  31. Added Prognostic Value of Cerebrospinal Fluid Biomarkers in Predicting Decline in Memory Clinic Patients in a Prospective Cohort. Handels, RL, Joore, MA, Vos, SJ, Aalten, P, Ramakers, IH, Rikkert, MO, Scheltens, P, Jansen, WJ, Visser, PJ, van Berckel, BM, van Domburg, P, Smid, M, Hoff, E, Hoogmoed, J, Bouwman, F, Claassen, J, Leentjens, AF, Wolfs, CA, Severens, JL, Verhey, FR. PubMed PMID:27031483
  32. Early cost-utility analysis of general and cerebrospinal fluid-specific Alzheimer's disease biomarkers for hypothetical disease-modifying treatment decision in mild cognitive impairment. Handels, RL, Joore, MA, Tran-Duy, A, Wimo, A, Wolfs, CA, Verhey, FR, Severens, JL. PubMed PMID:26071009
  33. Optimizing the use of expert panel reference diagnoses in diagnostic studies of multidimensional syndromes. Handels, RL, Wolfs, CA, Aalten, P, Bossuyt, PM, Joore, MA, Leentjens, AF, Severens, JL, Verhey, FR. PubMed PMID:25280531
  34. Health economic evaluation of treatments for Alzheimer's disease: impact of new diagnostic criteria. Wimo, A, Ballard, C, Brayne, C, Gauthier, S, Handels, R, Jones, RW, Jonsson, L, Khachaturian, AS, Kramberger, M. PubMed PMID:24605810
  35. Natural progression model of cognition and physical functioning among people with mild cognitive impairment and alzheimer's disease. Handels, RL, Xu, W, Rizzuto, D, Caracciolo, B, Wang, R, Winblad, B, Verhey, FR, Severens, JL, Fratiglioni, L, Joore, MA, Wimo, A. PubMed PMID:23948894
  36. Diagnosing Alzheimer's disease: a systematic review of economic evaluations. Handels, RL, Wolfs, CA, Aalten, P, Joore, MA, Verhey, FR, Severens, JL. PubMed PMID:23727080
  37. Impact of molecular imaging on the diagnostic process in a memory clinic. Ossenkoppele, R, Prins, ND, Pijnenburg, YA, Lemstra, AW, van der Flier, WM, Adriaanse, SF, Windhorst, AD, Handels, RL, Wolfs, CA, Aalten, P, Verhey, FR, Verbeek, MM, van Buchem, MA, Hoekstra, OS, Lammertsma, AA, Scheltens, P, van Berckel, BN. PubMed PMID:23164552
  38. Diagnostic and economic evaluation of new biomarkers for Alzheimer's disease: the research protocol of a prospective cohort study. Handels, RL, Aalten, P, Wolfs, CA, OldeRikkert, M, Scheltens, P, Visser, PJ, Joore, MA, Severens, JL, Verhey, FR. PubMed PMID:22883691
  39. Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI. Vos, S, van Rossum, I, Burns, L, Knol, D, Scheltens, P, Soininen, H, Wahlund, LO, Hampel, H, Tsolaki, M, Minthon, L, Handels, R, L'Italien, G, van der Flier, W, Aalten, P, Teunissen, C, Barkhof, F, Blennow, K, Wolz, R, Rueckert, D, Verhey, F, Visser, PJ. PubMed PMID:22264648
  40. Determinants of care costs of patients with dementia or cognitive impairment. Handels, RL, Wolfs, CA, Aalten, P, Verhey, FR, Severens, JL. PubMed PMID:22214890
  41. Biomarkers as predictors for conversion from mild cognitive impairment to Alzheimer-type dementia: implications for trial design. van Rossum, IA, Vos, S, Handels, R, Visser, PJ. PubMed PMID:20413876
Search PubMed

 

See all publications in PubMed or use the following query: handels r[au]

Full text are available on researchgate

 

Dissertation thesis (2014)

cover extra small

Download thesis

In the media: